Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.

Participative pricing demonstrates the basic idea of allowing customer participation in price-setting process. Nottingham Playhouse, IBIS Singapore, Metropolitan Museum of Art, Wiener Deewan, Girl Talk, 8k, Zest consulting, Radiohead band and many more have successfully implemented pay-what-you-want, the most innovative form of participative pricing. Based on the degree of participation, PWYW is the highest form that allows buyers to select any price they want to pay for a product/service, including zero. The present study examines how customers lower their motivation to (...) pay more for products offered under PWYW by morally disengaging themselves from reciprocity concerns. It focuses on one mechanism of moral disengagement—displacement of responsibility and tests the proposed hypotheses in PWYW context. 284 responses were gathered using structured questionnaires at a reputed public university. Data were analysed using partial least-squares structural equation modelling. Findings indicate that customers’ moral disengagement via displacement of responsibility towards reciprocity concerns is negatively associated with willingness-to-pay more. Results corroborate the attenuating role of perceived control on the negative association between displacement of responsibility towards reciprocity concerns and WTPM. However, relaxation from monetary commitments does not have a significant moderating effect on the negative relationship between moral disengagement and WTPM. This study is possibly the first to empirically investigate the interplay among individuals’ cognitive mechanisms, moral disengagement from reciprocity concerns and socio-demographic variables under participative pricing. Findings empirically substantiate the theory of moral disengagement, moral self-regulation and social cognitive theory. Practitioners should actively engage customers’ moral self-regulation process and provide more sense of perceived control while designing participative pricing offerings. (shrink)

Many states prohibit patients from appointing their physicians as health care proxies, fearing paternalism and conflict of interest. But the potential for conflict is not unique to physicians, and patients may have compelling reasons to prefer that their doctor make decisions on their behalf. Managing potential conflicts serves patients better than denying them the right to choose who will make health care decisions for them when they are no longer competent.

With the human genome mapped, and with the mapping of more than one hundred animal genomes in progress, the amount of genetic data available is increasing exponentially. This exponential increase in data is having an immediate impact on the process of drug development. By using techniques of information technology to manipulate data regarding the genes, proteins, and biochemical pathways associated with various diseases, scientists are beginning to be able to design drugs in a systematic fashion. In the context of any (...) given disease, scientists look to see whether a gene, a protein for which the gene codes, or another protein in the relevant biochemical pathway could be the “target” biological molecule, the “knocking out” of which would halt or slow the disease's progression. Once a target molecule has been identified and characterized structurally, drug therapies that would be likely to knock out this target can be identified and tested systematically. The merger of information technology and genetic technology has changed the process of pharmaceutical development so much that a new term—bioinformatics—has been coined to describe this new approach to such development. (shrink)

The Deese/Roediger–McDermott paradigm has been used extensively to examine false memory. During the study session, participants learn lists of semantically related items, referred to as targets. Critical lures are items which are also associated with the lists but are intentionally omitted from study. At test, when asked to remember targets, participants often report false memories for critical lures. Findings from experiments using the DRM show the ease with which false memories develop in the absence of suggestion or misinformation. Given this, (...) it is important to examine factors which influence the generalizability of the findings. One important factor is the persistence of false memory, or how long false memories last. Therefore, we conducted a systemic review to answer this research question: What is the persistence of false memory for specific items in the DRM paradigm? To help answer this question our review had two research objectives: to examine the trajectory of target memory and false memory for critical lures and to examine whether memory for targets exceeded false memory for critical lures. We included empirical articles which tested memory for the same DRM lists with at least two testing sessions. We discuss the results with respect to single-session delays, long-term memory recall and recognition, remember and know judgments for memory, and the effect of development, valence, warning, and connectivity on the trajectory of memory. Overall, the trajectory of targets showed a relatively consistent pattern of decrease across delay. The trajectory of critical lures was inconsistent. The proportion of targets versus critical lures across delay was also inconsistent. Despite the inconsistencies, we conclude that targets and critical lures have a dissimilar trajectory across delay and that critical lures are more persistent than targets. The findings with respect to long-term recall and recognition are consistent with both Fuzzy Trace Theory and Associative-Activation Theory of the DRM effect. The generation of false memory with brief delays is better explained by Associative-Activation Theory. Examining the connectivity between target items, and critical lures, and the effect that has during study and retrieval, can provide insight into the persistence of false memory for critical lures. (shrink)

We discuss the structure of Buddhist theory, showing that it is a kind of moral phenomenology directed to the elimination of egoism through the elimination of a sense of self. We then ask whether being raised in a Buddhist culture in which the values of selflessness and the sense of non-self are so deeply embedded transforms one’s sense of who one is, one’s ethical attitudes and one’s attitude towards death, and in particular whether those transformations are consistent with the predictions (...) that Buddhist texts themselves make. We discover that the effects are often significant, but not always expected. (shrink)

Kaum ein Buch hat so viele und so kontroverse Reaktionen verursacht wie Simone de Beauvoirs "Das Andere Geschlecht". Der Sammelband gibt einen Einblick in die aktuelle internationale Beauvoir-Debatte und die Art und Weise wie das fünfzigjährige Jubiläum des "Anderen Geschlechts" gefeiert wurde. Die Autorinnen versuchen die verschiedenen Grundthemen von Beauvoirs Werk, wie Geschlecht und Körper (D. Lamoureux, M. Couillard, M. L. Femenías), Gleichheit und Differenz (S. Kruks, Y. Raynova, S. Bainbrigge), Ausschluss und Anerkennung (D. Bergoffen, S. Moser), Verantwortung und Engagement (...) (F. Rétif, N. Bauer, K. Arp, Dauphin, C. Gater), aus der Perspektive der Gegenwart neu zu beleuchten. Darüber hinaus enthält der Band biographische (K. Vintges, B. Weisshaupt) und bibliographische Beiträge, die ihn zu einem Nachschlagewerk und zu einer Dokumentation der gegenwärtigen Beauvoirforschung werden lassen. Aus dem Inhalt: Françoise Rétif: Zur Aktualität von Simone de Beauvoir oder die Dialektik des Engagements - Nancy Bauer: First Philosophy, "The Second Sex", and the Third Wave - Debra Bergoffen: Simone de Beauvoir and Jean-Paul Sartre: Woman, Man and the Desire to be God - Elaine Stavro-Pearce: Transgressing Sartre: embodied situated subjects in "The Second Sex" - Susanne Moser: Subjekt und Anerkennung: Zum Problem des Ausschlusses von Frauen und Weiblichkeit im" Anderen Geschlecht" - Diane Lamoureux: Der Paradox des Körpers bei Simone de Beauvoir - Marie Couillard: Die Lesbierin bei Simone de Beauvoir und Nicole Brossard - María Luisa Femenías: Beauvoir revisited: Butler and the "gender" question - Sonia Kruks: Panopticism and Shame: Reading Foucault through Beauvoir - Yvanka B. Raynova: Für eine postmoderne Ethik der Gerechtigkeit: Simone de Beauvoir und Jean-François Lyotard - Kristana Arp: Moral obligation in Simone de Beauvoir's "The Ethics of Ambiguity" - Susan Bainbrigge: The Impact of Simone de Beauvoir's "universel singularisé" on the Politics of Representation and the Representation of Politics - Sandrine Dauphin: From Socialism to radical Feminism: Militant foundations in Simone de Beauvoir's Writings - Claudia Gather: Simone de Beauvoir, eine Klassikerin der feministischen Soziologie? - Karen Vintges: Beauvoir's autobiography: "autofiction" or selftechnique? - Brigitte Weisshaupt: Simone de Beauvoir und Jean-Paul Sartre. Eine Anmerkung - Susanne Moser/Yvanka B. Raynova: "50 Jahre 'Das andere Geschlecht'": Zur internationalen Konferenz in Paris (19.-23.01.1999). (shrink)

[1] Yotse la-or ʻal yede ṭalmidaṿ shomʻe liḳḥo be-yerakh ha-eṭanim di-shenaṭ 2016 -- [2] Yotse la-or ʻal yede ṭalmidaṿ shomʻe liḳḥo be-yerakh ha-eṭanim di-shenaṭ 2018.

Buddhist concepts of personal life and responsibilities.

India has been independent for 70 years now, and it is a good time to reflect on the political philosophy that underwrote the movement that gained that independence. When we do so, we discover the origins of a political vocabulary that is still in use today, although sadly not used with the same rigor and precision with which it was used then. We also find that those who recur to Indian political thought from the pre-independence period tend to return to (...) a single strand of that thought—the theorization of ahimsa by Mohandas K. Gandhi, as for instance in the recent essay on Indian political thought in The New York Times by Gopalkrishna Gandhi (Gandhi won’t leave India 2017). In this discussion, we hope to draw attention to some of the less well-known resources offered by pre-independence Indian philosophy and in particular the political thought of the Arya samaji Congressman, philosopher and political activist, Lajpat Rai. His political philosophy is important for understanding the theorization of and debates within the Indian independence movement; we think that it also suggests ways to think about contemporary political and revolutionary movements and merits consideration in current debates in political philosophy. (shrink)

El artículo expone el significado y los objetivos de la Estética hermenéutica, representada en la filosofía de Gadamer, y de la Hermenéutica de la imagen, representada por la Teoría del arte de Boehm. Ambas propuestas tienen sus raíces en la filosofía y el arte contemporáneos, pero permiten una experiencia nueva de la Historia del arte en general. El interés de ambas propuestas se resume en dos aspectos: evitar aislar la imagen de la comprensión en que siempre nos movemos, y evitar (...) que el forzoso lenguaje discursivo de la interpretación suplante la imagen artística. (shrink)

La nueva ley de bioética en Francia, propuesta en 2019 y aprobada por la Asamblea Nacional el 29 de junio de 2021, introduce en su artículo primero, relativo a las Tecnologías de Reproducción Artificial (ART por sus siglas en inglés), modificaciones al artículo L. 2141-2 y L. 2141-3 de la ley número 2011-814 de 7 de julio de 2011 relativa a la bioética. Abre así el camino a “cualquier pareja formada por un hombre o una mujer o por dos mujeres (...) o cualquier mujer soltera”. Como resultado, se rompe el vínculo entre el derecho y la bioética. Mientras que el derecho debe proteger el interés individual, la bioética le recuerda al derecho que también debe protegerse el bien común. De ahí las siguientes interrogantes que surgen a raíz de esta nueva ley de bioética: ¿las ART son un derecho para todos? ¿Es legítimo reivindicarlo en nombre de la igualdad? ¿Qué pasa con la justicia? En este artículo me gustaría abordar el tema desde un punto de vista biojurídico, situando el problema en el marco de la filosofía del derecho. (shrink)

There is an error in the completeness proof for the {λ, =} part of FOIL-K. The error occurs in Section 4, in the text following the proof of Corollary 4.7, and concerns the definition of the interpretation I on relation symbols. Before this point in the paper, for each object variable v an equivalence class v has been defined, and for each intension variable f a function f has been defined. Then the following definition is given for a relation symbol (...) P : v1, v2, . . . , f1, f2, . . . ∈ I(P )(Γ) just in case there are w1, w2, . . . in d(Γ) with wi ∈ vi such that P (w1, w2, . . . , f1, f2, . . .) ∈ Γ. It was pointed out by Torben Brauner that we could have f1 and g1 being the same function, but also have P (w1, w2, . . . , f1, f2, . . .) ∈ Γ without having P (w1, w2, . . . , g1, f2, . . .) ∈ Γ. Our solution is to modify the definition of the model, rather artificially, so that if f and g are the same function, then f and g are syntactically the same intension variable. This is done as follows. First, arbitrarily choose some object variable w, and its corresponding equivalence class w. For each intension variable f we define a disambiguation world ˆ. (shrink)

La vida cotidiana y la cultura contemporáneas experimentan un alto grado de estetización que parece hacer superfluo el arte. El presente artículo responde a esta problemática y plantea la pregunta por la función del arte en la sociedad moderna, e ilustra el debate con las tesis de W. Welsch, R. Bubner, J. Ritter, O. Marquard y K. Konig. El artículo se inclina por las tesis de Marquard, quien aboga por un arte estético contra un arte escatológico. Sólo un arte estético (...) como "organon" de la experiencia puede compensar la pérdida de percepción, de juicio autónomo y el fomento de la ficción que genera el poder de los medios en la cultura actual. Un arte escatológico como "organon" de la idea, por el contrario, se hace cómplice de dicha perversión cultural. (shrink)

Cuando se habla de filosofía se habla de antropología. Del mismo modo, cuando se habla de antropología también se debería de hablar de la afectividad. Sin embargo, hasta hoy, pienso que muchos filósofos han comprendido mal la afectividad en la persona humana, pues han caído en dos reduccionismos: uno considera la afectividad como un componente irracional, es el caso del dualismo; el otro la asocia a un monismo, como se puede verificar en el sentimentalismo y en el psicologismo. De igual (...) modo, aquellos que permanecen en una posición intermedia también la han comprendido mal, como se puede ver, por ejemplo, en la perspectiva aristotélico- tomista. Para estos, la afectividad es siempre pre- moral y debe ser siempre subordinada a la razón y a la voluntad. De esta forma, no han comprendido que la afectividad tiene también un ámbito espiri-tual y que, así, es ella quien muchas veces debe integrar la razón y la voluntad, a fin de garantizar la autorrea-lización de la persona humana. En este sentido, tampoco han visto que la afectividad puede ser valorada desde el punto de vista moral. Debido sobre todo a estos errores que se han cometido en el ámbito filosófico con relación a la afectividad, he visto que sería bueno repensar la noción de afectividad de la persona humana. Así, de entre todos los autores que he conocido y estudiado, he visto que la propuesta de Dietrich von Hildebrand con relación a la afectividad podría proporcionar muchas respuestas y herramientas para poder solventar estas inquietudes filosóficas y poder evitar reduccionismos, proporcionando interpretaciones más completas. El filósofo, fenomenólogo-realista, Dietrich von Hildebrand se ha distinguido en muchas áreas de la filosofía, como en la metafísica, en la gnoseología, en la ética, en la antropología, en la religión, etc.. “Casi quiero decir que el genio (artístico) de Adolf von Hildebrand ha sido heredado por su hijo (...) como un genio filo-sófico” (Husserl: H. Sepp; L. Embree, Handbook of Phenomenological Aesthetics, Springer, London, 2010, p. 145 (Traducción del autor). No obstante, sin duda alguna, la principal área, aquella en la que con mayor prominencia ha destacado, creemos que fue en el ámbito de la afectividad, aportando, así, contribuciones que hasta hoy no hubieran sido tenidas en consideración. Husserl lo comprueba. Cuando ha dirigido la tesis de doctorado de Hildebrand ha decido: “Sin embargo, su verdadera fuerza y sus significativos y originales resul-tados residen principalmente en la esfera emocional, en los análisis que llenan los capítulos 3o a 8o, de la parte II, y que sorprenden con un conocimiento íntimo sin precedentes de las múltiples formas de la conscien-cia emocional y sus correlatos representativos. Dicho esto, sólo puedo solicitar el título de opus eximium para esta importante obra” [E. Husserl, Urteil Über Hildebrands Doktorarbeit, Ed. K. Schuhmann, Aletheia, V, 1992, p. 5 (Traducción al español del autor)]. El mapa afectivo en Hildebrand es muy vasto. Por esto, he decidido presentar directamente un solo tema, o sea de que modo la afectividad se relaciona con la libertad y así, en este sentido, como ella puede ser valorada moralmente. Para atingir este objetivo, inicialmente me propongo analizar como Hildebrand entiende y concibe la afectividad en la persona humana. Posteriormente analizaré la libertad humana y su relación con la moralidad. Finalmente relacionaré los distintos tipos de libertad en la persona humana con la afectividad, demostrando así al mismo tiempo como la afectividad puede ser moralmente evaluada. (shrink)

We created paired moral dilemmas with minimal contrasts in wording, a research strategy that has been advocated as a way to empirically establish principles operative in a domain‐specific moral psychology. However, the candidate “principles” we tested were not derived from work in moral philosophy, but rather from work in the areas of consumer choice and risk perception. Participants were paradoxically less likely to choose an action that sacrifices one life to save others when they were asked to provide more reasons (...) for doing so (Experiment 1), and their willingness to sacrifice lives depended not only on how many lives would be saved, but on the number of lives at risk (Experiment 2). The latter effect was also found in a within‐subjects design (Experiment 3). These findings suggest caution in the use of artificial dilemmas as a key testbed for revealing principled bases for moral judgment. (shrink)

This book discusses a variety of world views that we can find to describe human relationships with the environment, and the underlying values in them. It reviews existing international legal instruments discussing some of the ethical values that have been agreed among member states of the United Nations.

Healthcare reforms in India have been a much-debated issue in the recent past. While the debate has focused mainly on the right to healthcare, another by-product that has evolved out of the debate was the current problem of medical malpractice and the healthcare law. The last decade has seen an increase in the healthcare facilities in the country. This, however, has come with a bulk of medical error cases which the courts have entertained. According to reports, there has been an (...) increase in medical litigation cases by 400% in the last decade. There are about 5.2 million cases of medical error in the country every year. While there exists a standard legal system in the country which entertains such complaints of medical malpractice, the attempt by regulators and medical practitioners should be to reduce these cases. This paper seeks to analyze the extent to which medical malpractice cases affect consumers. It analyzes the existing medical liability system which has mainly evolved through the jurisprudence laid down by the English courts and critiques it. It also looks into the major reasons for such medical mishaps. Authors argue that a “No-Fault” system may give better outcomes. They analyze this by looking at the no-fault liability model implemented in New Zealand. Narratives of no-fault liability being implemented in India have also been used. These are showcased from instances of Motor Vehicles Act, 1988, and Clinical Trial regulations. It is also argued that a by-product of a no-fault liability system is stringent regulations which are used to reduce the possibility of medical mishaps altogether. Lastly, the possible problems of the no-fault liability system are discussed in the paper. (shrink)

Most psychological research consists of experiments that put people in artificial situations that elicit unnatural behavior whose ecological validity is unknown. Without knowing the psychocultural meaning of experimental situations, we cannot interpret the responses of WEIRD people, let alone people in other cultures. Psychology, like other sciences, needs to be solidly rooted in naturalistic observation and description of people around the world. Theory should be inductively developed and tested against real-world behavior.

Moral hypocrisy is typically viewed as an ethical accusation: Someone is applying different moral standards to essentially identical cases, dishonestly claiming that one action is acceptable while otherwise equivalent actions are not. We suggest that in some instances the apparent logical inconsistency stems from different evaluations of a weak argument, rather than dishonesty per se. Extending Corner, Hahn, and Oaksford's (2006) analysis of slippery slope arguments, we develop a Bayesian framework in which accusations of hypocrisy depend on inferences of shared (...) category membership between proposed actions and previous standards, based on prior probabilities that inform the strength of competing hypotheses. Across three experiments, we demonstrate that inferences of hypocrisy increase as perceptions of the likelihood of shared category membership between precedent cases and current cases increase, that these inferences follow established principles of category induction, and that the presence of self-serving motives increases inferences of hypocrisy independent of changes in the actions themselves. Taken together, these results demonstrate that Bayesian analyses of weak arguments may have implications for assessing moral reasoning. (shrink)

Mammalian telomeres have evolved safeguards to prevent their recognition as DNA double‐stranded breaks by suppressing the activation of various DNA sensing and repair proteins. We have shown that the telomere‐binding proteins TRF2 and RAP1 cooperate to prevent telomeres from undergoing aberrant homology‐directed recombination by mediating t‐loop protection. Our recent findings also suggest that mammalian telomere‐binding proteins interact with the nuclear envelope to maintain chromosome stability. RAP1 interacts with nuclear lamins through KU70/KU80, and disruption of RAP1 and TRF2 function result in (...) nuclear envelope rupture, promoting telomere‐telomere recombination to form structures termed ultrabright telomeres. In this review, we discuss the importance of the interactions between shelterin components and the nuclear envelope to maintain telomere homeostasis and genome stability. (shrink)

Operational and financial sustainability have, over time, remained as issues in the microfinance industry. The microfinance industry is struggling to gain self-sufficiency in Pakistan due to non-performing loans and operating costs. Simultaneously, deliberation on corporate social responsibility is also considered in academic literature and organizational practices. However, studies on CSR and financial performance in the microfinance sector are scarce, especially in Pakistan. CSR will develop customer attraction and loyalty, employee attraction, motivation and commitment, MFIs' reputation and access to capital, and (...) eventually build financial performance. Interviews were conducted with branch managers of microfinance institutions to test previous questionnaires. A self-administered survey was conducted to collect data from the managers of the microfinance banks operating in Punjab. Descriptive and inferential statistics were performed to answer research questions using Smart PLS. Most of the microfinance institutions believe in social responsibilities but lacks fund allocation and approval from higher management, and results are in line with prior studies. These empirical findings lead to the perception that CSR is not a barrier performance in microfinance banks as they have access to capital. The results indicated a strong positive correlation between CSR and the financial performance of the MFIs. CSR also positively correlates with customer retention, employees' motivation and attraction, and business reputation. CSR was associated with access to capital but was found to be weak. The research also narrated the limitation and practical implications of the study. The study also discusses further research directions. (shrink)

By examining evidence from India, where quotas for women in local government were introduced in 1993, this article argues that institutional reform can disturb hegemonic discourses sufficiently to open a window of opportunity where deliberative democratic norms take root and where, in addition to the politics of recognition, the politics of redistribution also operates.

The Fourth Edition of this bestselling, highly regarded book has been fully revised to incorporate changes in law and clinical guidance making a vital impact on patient management, encompassing: The Equalities Act 2010 which provides a right of older people to treatment without discrimination ; Case law on withdrawing nutrition and hydration ; Updated guidance on resuscitation from the Resuscitation Council, the British Medical Association and the Royal College of Nursing ; The redefining of good medical practice by the General (...) Medical Council ; The abolition of the Liverpool Care Pathway with an updated guidance on end of life care and advance care planning. Expanded throughout, this new edition also integrates two entirely new chapters covering testamentary capacity and role of the physician, and religious beliefs and end of life issues. Its practical, reflective and informative approach continue to make it essential reading for all health professionals, particularly trainees, involved in making difficult decisions in the care of older persons. It is also highly recommended for undergraduate medical students. (shrink)